Sema Weight Loss
A once-weekly GLP-1 injection that helps curb appetite, slow digestion, and keep you feeling full longer, so eating less feels easier.
- Once-weekly injection
- Dose increased gradually
- Individualized by your physician
Physician-guided GLP-1 weight loss with Sema o Tirzep, prescribed online by board-certified physicians and shipped to your door in discreet packaging.

Every body is different. That’s why our physicians offer more than one GLP-1 weight loss medication, each tailored to your goals, lifestyle, and budget.
A once-weekly GLP-1 injection that helps curb appetite, slow digestion, and keep you feeling full longer, so eating less feels easier.
A once-weekly dual-action injection that works on two hunger and blood-sugar hormones, GLP-1 and GIP, for people who want a next-generation option.
Prescription required. Not everyone qualifies. Your physician decides which medication, if any, is right for you. Important Safety Information

Not sure whether Sema or Tirzep fits you better? Complete one questionnaire and your physician will recommend the right medication and dose for your health history.
Now with even more ways to make it work for you. We know that every body is different, which is why our team offers multiple treatment options, each tailored to your goals, lifestyle, and budget.
Whether you’re just getting started or continuing treatment, we’re here to make it simple, effective, and stress-free.

No pressure. No complicated hoops. Just real help, from real people who care.
Answer a secure online questionnaire about your health, weight, and goals. It only takes a few minutes.
Board-certified physicians will review and, if you are a candidate, create an individualized plan for you. You will not be charged if you are not a candidate.
The medication will be mailed to you in discreet packaging. You will be on your way to being the best you.
Both are once-weekly prescription injections used for medical weight loss. Here’s a simple side-by-side look. Your physician makes the final recommendation based on your health history.
Not sure which fits? Your physician recommends the medication and dose after reviewing your health history.


A SimpleFix weight loss patient shares her journey, from 208 lbs to 182 lbs, and feeling amazing. Her physician-guided plan paired a once-weekly GLP-1 with small, steady changes to how she eats and moves.
Individual results vary and are not guaranteed. Weight loss depends on your health, dose, diet, and activity.
Background in Family Practice and Sports Medicine, with a focus on weight management, aesthetics and regenerative medicine.
Weight loss is one part of feeling your best. Explore our other physician-reviewed programs for thinning hair, skin, energy, and everyday health.
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Thinning hair
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Sexual health
Pills, a weekly patch, emergency contraception, and more, reviewed by a licensed physician.
Emergency antibiotic kit
A physician-reviewed prescription kit for travel, storms, and pharmacy disruptions.
Skin rejuvenation
A daily skin care collection to keep skin glowing while you lose weight.
Have something else on your mind? Text us any time — our team is happy to help.
SimpleFixRx connects patients with licensed providers for evaluation of weight-management treatment. If medication is appropriate, the provider discusses treatment options, benefits, risks and follow-up. Your provider determines the evaluation and follow-up you need based on your health history, treatment and the requirements where you are physically located. A live video or phone visit, testing or an in-person examination may be required. Completing a questionnaire or making a payment does not guarantee a prescription.
Sema and Tirzep refer to different prescription medications with different active ingredients. They are not interchangeable, and dose instructions must not be transferred from one product or concentration to another. Your clinician will identify the exact medication, whether it is FDA-approved or compounded, and its intended use before treatment. See the side-by-side comparison.
Yes. GLP-1 prescription treatment requires an appropriate evaluation and a valid prescription from an authorized clinician. Not everyone qualifies. Your provider determines the evaluation and follow-up you need based on your health history, treatment and the requirements where you are physically located. A live video or phone visit, testing or an in-person examination may be required. Completing a questionnaire or making a payment does not guarantee a prescription.
Eligibility is decided by an independent licensed provider, not by payment. Review the program’s checkout terms for any consultation fees, payment authorizations and refund conditions before submitting an order. If treatment is not prescribed, contact our team to confirm how those terms apply to your transaction.
There is no guaranteed amount or speed of weight loss. Outcomes depend on the individual, the specific medication and treatment plan, and other health and lifestyle factors. Your clinician will discuss realistic expectations and monitor your response; published results for one product do not establish results for another.
Side effects vary by medication and can include nausea, vomiting, diarrhea, constipation and abdominal discomfort. Serious risks are also possible. Read the information supplied for your exact prescription and discuss your medical history, other medicines and pregnancy plans with your clinician. Contact your clinician promptly about concerning symptoms, and seek emergency care for severe symptoms.
You may request a treatment review. Share the exact medication, formulation, concentration, dose, last dose date, prescribing records and any side effects. A clinician decides whether continuation, a change or an in-person assessment is appropriate. Do not switch products or reuse dose-conversion instructions without your clinician’s direction.
Shipping is arranged only after any required prescription is approved and the dispensing pharmacy completes its review. Availability, carrier and delivery timing depend on the medication, pharmacy and destination. Follow your pharmacy’s storage instructions and contact the pharmacy before using medication that arrives damaged or outside its storage requirements.
Compounded medications are not FDA-approved. FDA does not review them for safety, effectiveness or quality before marketing, and they are not FDA-approved generic equivalents of branded medicines. A compounded medication should be considered only when a patient’s medical needs cannot be met by an FDA-approved product. Read the FDA’s information on unapproved GLP-1 drugs.
Visit our FAQ page for general questions, or learn about SimpleFixRx and our physicians. Text (682) 245-2031 to reach our team or request a conversation with your provider. For personal treatment advice, speak with your prescribing clinician rather than relying on general website information.
Complete the health questionnaire in minutes. If you’re a candidate, a board-certified physician creates your individualized Sema or Tirzep plan. You won’t be charged if you’re not a candidate.
Log in to your patient portal, or explore more about SimpleFixRx.

Sema and Tirzep quiet food noise and help you feel full sooner. Pair them with protein-rich meals, water, and daily movement to protect muscle and keep the weight off.
Board-certified in Obstetrics and Gynecology and a Fellow of the American College of Obstetricians and Gynecologists.